Polypoidal choroidal vasculopathy and systemic lupus erythematosus.

Journal Article (Journal Article)

Systemic lupus erythematosus (SLE) associated with antiphospholipid syndrome can have ocular complications. We report a 44-year-old Chinese lady with recurrent relapses of SLE and antiphospholipid syndrome with high disease activity, presenting with visual distortion in her right eye for 2 months. There was subretinal hemorrhage in her right eye, confirmed on investigations to be choroidal neovascularization secondary to a variant of age-related macular degeneration known as polypoidal choroidal vasculopathy (PCV). Anti-vascular endothelial growth factor therapy resolved her eye condition. SLE could be associated with PCV via common mechanisms, including complement pathway activation and vasculitis involving the choroidal circulation.

Full Text

Duke Authors

Cited Authors

  • Chin, YC; Bhargava, M; Khor, CC; Cheung, CMG; Wong, TY

Published Date

  • March 2014

Published In

Volume / Issue

  • 23 / 3

Start / End Page

  • 319 - 322

PubMed ID

  • 24407425

Electronic International Standard Serial Number (EISSN)

  • 1477-0962

Digital Object Identifier (DOI)

  • 10.1177/0961203313519160


  • eng

Conference Location

  • England