THALIA - An automatic hierarchical analysis system to detect drusen lesion images for amd assessment


Conference Paper

Age-related macular degeneration (AMD) is a leading cause of permanent blindness. In its early stage AMD is characterized by drusen which are extracellelur deposits in the retina. In this paper, we present THALIA, an automatic system for the detection of drusen images for AMD assessment. First, the macular region of interest is detected using a seeded mode tracking approach. The macular region of interest is then mapped into a new representation using a hierarchicial word transform (HWI). In HWI, dense sampling is first carried out to generate structured pixels which embed local context. These structured pixels are then clustered using hierarchical k-means. The HWI image is subsequently classified using a SVM-based classifier. We have tested THALIA on a dataset of 350 images and obtained an accuracy of 95.46%. Results are promising for further validation of the THALIA system. © 2013 IEEE.

Full Text

Duke Authors

Cited Authors

  • Wong, DWK; Liu, J; Cheng, X; Zhang, J; Yin, F; Bhargava, M; Cheung, GCM; Wong, TY

Published Date

  • August 22, 2013

Published In

Start / End Page

  • 884 - 887

Electronic International Standard Serial Number (EISSN)

  • 1945-8452

International Standard Serial Number (ISSN)

  • 1945-7928

International Standard Book Number 13 (ISBN-13)

  • 9781467364546

Digital Object Identifier (DOI)

  • 10.1109/ISBI.2013.6556617

Citation Source

  • Scopus