Superpixel classification for initialization in model based optic disc segmentation.

Journal Article (Journal Article)

Optic disc segmentation in retinal fundus image is important in ocular image analysis and computer aided diagnosis. Because of the presence of peripapillary atrophy which affects the deformation, it is important to have a good initialization in deformable model based optic disc segmentation. In this paper, a superpixel classification based method is proposed for the initialization. It uses histogram of superpixels from the contrast enhanced image as features. In the training, bootstrapping is adopted to handle the unbalanced cluster issue due to the presence of peripapillary atrophy. A self-assessment reliability score is computed to evaluate the quality of the initialization and the segmentation. The proposed method has been tested in a database of 650 images with optic disc boundaries marked by trained professionals manually. The experimental results show an mean overlapping error of 10.0% and standard deviation of 7.5% in the best scenario. The results also show an increase in overlapping error as the reliability score reduces, which justifies the effectiveness of the self-assessment. The method can be used for optic disc boundary initialization and segmentation in computer aided diagnosis system and the self-assessment can be used as an indicator of cases with large errors and thus enhance the usage of the automatic segmentation.

Full Text

Duke Authors

Cited Authors

  • Cheng, J; Liu, J; Xu, Y; Yin, F; Wong, DWK; Lee, B-H; Cheung, C; Aung, T; Wong, TY

Published Date

  • 2012

Published In

  • Annu Int Conf Ieee Eng Med Biol Soc

Volume / Issue

  • 2012 /

Start / End Page

  • 1450 - 1453

PubMed ID

  • 23366174

Electronic International Standard Serial Number (EISSN)

  • 2694-0604

Digital Object Identifier (DOI)

  • 10.1109/EMBC.2012.6346213


  • eng

Conference Location

  • United States