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Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey.

Publication ,  Journal Article
Foster, PJ; Wong, TY; Machin, D; Johnson, GJ; Seah, SKL
Published in: Br J Ophthalmol
September 2003

AIM: To describe risk factors for nuclear, cortical, and posterior subcapsular (PSC) cataracts in Chinese Singaporeans. METHODS: A population based cross sectional study was carried out on ethnic Chinese men and women aged 40-81 years. A stratified, clustered, disproportionate (more weights to older people), random sampling procedure was used to initially select 2000 Chinese names of those aged 40-79 years from the 1996 electoral register in the Tanjong Pagar district in Singapore. Eligible subjects (n = 1717) were invited for a standardised ocular examination and interview at a centralised clinic, following which an abbreviated examination was conducted for non-respondents in their homes. Cataract was graded clinically using to the Lens Opacity Classification System (LOCS) III system. The main outcome measures were adjusted odds ratio for risk factors for specific cataract types (nuclear, cortical and PSC), any cataract and cataract surgery, examined in multiple logistic regression models. RESULTS: Out of the 1232 (71.8%) examined, 1206 (70.2%) provided lens data for this analysis. Increasing age was associated with all cataract types, any cataract, and cataract surgery. There was no significant sex difference in presence of any cataract, specific cataract types or cataract surgery. After controlling for age, sex, and other factors, diabetes was associated with cortical cataract (3.1; 95% CI: 1.6 to 6.1), PSC cataract (2.2; 95% CI 1.2 to 4.1), any cataract (2.0; 95% CI: 0.9 to 4.5), and cataract surgery (2.3; 95% CI: 1.3 to 4.1). Lower body mass index was associated with cortical cataract (1.8; 95% CI: 1.1 to 2.9; lowest versus highest quintile) and any cataract (2.3; 95% CI: 1.3 to 4.0). Current cigarette smoking was associated with nuclear cataract (1.7, 95% CI: 1.0 to 2.9; more than 10 cigarettes per day versus none). A non-professional occupation was associated with nuclear cataract (2.9; 95% CI: 1.5 to 5.8; for production or machine operators and 2.6; 95% CI: 1.2 to 5.5; for labourers or agricultural workers, both versus professionals). Lower education was associated with nuclear cataract (2.3; 95% CI: 1.0 to 5.2, none versus tertiary), while lower household income was associated with PSC cataract (4.7, 95% CI: 1.1 to 20.0; income

Duke Scholars

Published In

Br J Ophthalmol

DOI

ISSN

0007-1161

Publication Date

September 2003

Volume

87

Issue

9

Start / End Page

1112 / 1120

Location

England

Related Subject Headings

  • Socioeconomic Factors
  • Smoking
  • Singapore
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Epidemiologic Methods
  • Diabetes Mellitus
 

Citation

APA
Chicago
ICMJE
MLA
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Foster, P. J., Wong, T. Y., Machin, D., Johnson, G. J., & Seah, S. K. L. (2003). Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey. Br J Ophthalmol, 87(9), 1112–1120. https://doi.org/10.1136/bjo.87.9.1112
Foster, P. J., T. Y. Wong, D. Machin, G. J. Johnson, and S. K. L. Seah. “Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey.Br J Ophthalmol 87, no. 9 (September 2003): 1112–20. https://doi.org/10.1136/bjo.87.9.1112.
Foster PJ, Wong TY, Machin D, Johnson GJ, Seah SKL. Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey. Br J Ophthalmol. 2003 Sep;87(9):1112–20.
Foster, P. J., et al. “Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey.Br J Ophthalmol, vol. 87, no. 9, Sept. 2003, pp. 1112–20. Pubmed, doi:10.1136/bjo.87.9.1112.
Foster PJ, Wong TY, Machin D, Johnson GJ, Seah SKL. Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey. Br J Ophthalmol. 2003 Sep;87(9):1112–1120.

Published In

Br J Ophthalmol

DOI

ISSN

0007-1161

Publication Date

September 2003

Volume

87

Issue

9

Start / End Page

1112 / 1120

Location

England

Related Subject Headings

  • Socioeconomic Factors
  • Smoking
  • Singapore
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Epidemiologic Methods
  • Diabetes Mellitus