Retinal vein occlusion: an approach to diagnosis, systemic risk factors and management.

Journal Article (Journal Article;Review)

Retinal vein occlusion (RVO) is the second most common retinal vascular disease after diabetic retinopathy and is a common cause of visual morbidity and blindness in the elderly. A large proportion of patients with RVO have a history of cardiovascular disease, hypertension, diabetes mellitus or open-angle glaucoma. Although RVO is sometimes associated with thrombophilias and coagulation abnormalities, the role of coagulation factors in the development of RVO remains unclear. This review did not find strong evidence to support an extensive work-up for thrombophilic and coagulation diseases for the vast majority of patients. However, when tests for common cardiovascular risk factors for RVO are negative, evaluation for potential coagulation disorders may be indicated, particularly in young patients and in patients with bilateral RVO, a history of previous thromboses or a family history of thrombosis.

Full Text

Duke Authors

Cited Authors

  • Yau, JWY; Lee, P; Wong, TY; Best, J; Jenkins, A

Published Date

  • December 2008

Published In

Volume / Issue

  • 38 / 12

Start / End Page

  • 904 - 910

PubMed ID

  • 19120547

Electronic International Standard Serial Number (EISSN)

  • 1445-5994

Digital Object Identifier (DOI)

  • 10.1111/j.1445-5994.2008.01720.x


  • eng

Conference Location

  • Australia