Reliability of computer-assisted retinal vessel measurementin a population.

Conference Paper

The purpose of the study was to assess the intergrader and intragrader reliability of computer-assisted retinal vessel dia-meter measurement in a defined, community-based population. Retinal photographs from participants in the Blue Mountains Eye Study were digitized using standard techniques. A grader identified all retinal vessels located 0.5-1.0 disc diameter from the optic disc margin,and a computer program measured the width of these vessels. Intergrader and intragrader reliability was assessed on a random sub-sample of 184 and 97 images, respectively, using quadratic weighted kappa(kappa) and correlation analysis (R2). Intergrader reliability was high for summary indices of retinal arteriolar (kappa = 0.85, R2 = 0.88)and venular (kappa = 0.90, R2 = 0.90)diameters, and their ratio, the arteriole-to-venule ratio (kappa = 0.75, R2 = 0.79).Intragrader reliability was also high, with kappa values ranging from 0.80 to 0.93 and from 0.80 to 0.92 for graders 1 and 2, respectively. It is concluded that the retinal vessel diameters could be reliably measured using computer-assisted software and may be used for population-based research.

Full Text

Duke Authors

Cited Authors

  • Sherry, LM; Wang, JJ; Rochtchina, E; Wong, T; Klein, R; Hubbard, L; Mitchell, P

Published Date

  • June 2002

Published In

Volume / Issue

  • 30 / 3

Start / End Page

  • 179 - 182

PubMed ID

  • 12010210

Electronic International Standard Serial Number (EISSN)

  • 1442-9071

International Standard Serial Number (ISSN)

  • 1442-6404

Digital Object Identifier (DOI)

  • 10.1046/j.1442-9071.2002.00520.x