Changing indications for penetrating keratoplasty: a newly developed country's experience.

Journal Article (Journal Article)

PURPOSE: To study the changing indications for penetrating keratoplasty in Singapore and compare local indications with developed countries with established corneal graft programs. METHODS: A descriptive study of all penetrating keratoplasty cases performed in the Singapore National Eye Center over a 5 year period, from 1 January 1991 to 31 December 1995 using records of the Singapore Eye Bank registry. RESULTS: A total of 327 penetrating keratoplasties were performed. Bullous keratopathy was the indication in more than a quarter of all cases (26.3%). Aphakic bullous keratopathy (11.6%) and pseudophakic bullous keratopathy (11.3%) accounted for the majority of the bullous keratopathy cases. The other leading indications were regrafts (11.9%), corneal dystrophies (10.4%), traumatic scarring (10.1%) and keratoconus (9.8%). A higher proportion of aphakic and pseudophakic bullous keratopathy as well as regrafts was noted in this series compared to a previous report on corneal transplantation in the 1980s. A rising indication rate of pseudophakic bullous keratopathy, in conjunction with a declining indication rate of herpetic keratitis was observed over the 5 year study period. CONCLUSIONS: The indications for penetrating keratoplasty in Singapore appear to follow the trend seen in developed Western countries over the past few decades.

Full Text

Duke Authors

Cited Authors

  • Wong, TY; Chan, C; Lim, L; Lim, TH; Tan, DT

Published Date

  • May 1997

Published In

Volume / Issue

  • 25 / 2

Start / End Page

  • 145 - 150

PubMed ID

  • 9267601

International Standard Serial Number (ISSN)

  • 0814-9763

Digital Object Identifier (DOI)

  • 10.1111/j.1442-9071.1997.tb01296.x


  • eng

Conference Location

  • Australia