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A cohort study of incident myopia in Singaporean children.

Publication ,  Journal Article
Saw, S-M; Shankar, A; Tan, S-B; Taylor, H; Tan, DTH; Stone, RA; Wong, T-Y
Published in: Invest Ophthalmol Vis Sci
May 2006

PURPOSE: To determine the risk factors of incident myopia in a school-based cohort study in Singaporean children. METHODS: A 3-year prospective cohort study was conducted in Singaporean school children aged 7 to 9 years in three schools at entry. Chinese children without myopia at baseline (n = 994) were included in the analysis. The main outcome was incident myopia, defined as spherical equivalent (SE) at least -0.75 D based on cycloplegic autorefraction. Other definitions of incident myopia, at least -0.5 D and at least -1.0 D, were also assessed. RESULTS: After controlling for school, age, gender, income, reading in books per week and intelligence quotient (IQ) test scores, we found the relative risk (RR) of incident myopia defined as -0.75 D to be 1.55 (95% confidence interval [CI] 1.18-2.04) for two versus no myopic parents. The multivariate RR of myopia for IQ in the third versus first tertile was 1.50 (95% CI, 1.19-1.89). However, the RR of incident myopia was 1.01 (95% CI, 0.97-1.05) for every unit increase in books read per week. Similar results were obtained with definitions of -0.5 and -1.0 D for incident myopia. CONCLUSIONS: These data provide new prospective evidence of essential links between parental myopia, IQ scores and subsequent myopia development. However, reading in books per week was not associated with incident myopia.

Duke Scholars

Published In

Invest Ophthalmol Vis Sci

DOI

ISSN

0146-0404

Publication Date

May 2006

Volume

47

Issue

5

Start / End Page

1839 / 1844

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Singapore
  • Risk Factors
  • Risk
  • Ophthalmology & Optometry
  • Myopia
  • Male
  • Intelligence Tests
  • Incidence
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Saw, S.-M., Shankar, A., Tan, S.-B., Taylor, H., Tan, D. T. H., Stone, R. A., & Wong, T.-Y. (2006). A cohort study of incident myopia in Singaporean children. Invest Ophthalmol Vis Sci, 47(5), 1839–1844. https://doi.org/10.1167/iovs.05-1081
Saw, Seang-Mei, Anoop Shankar, Say-Beng Tan, Hugh Taylor, Donald T. H. Tan, Richard A. Stone, and Tien-Yin Wong. “A cohort study of incident myopia in Singaporean children.Invest Ophthalmol Vis Sci 47, no. 5 (May 2006): 1839–44. https://doi.org/10.1167/iovs.05-1081.
Saw S-M, Shankar A, Tan S-B, Taylor H, Tan DTH, Stone RA, et al. A cohort study of incident myopia in Singaporean children. Invest Ophthalmol Vis Sci. 2006 May;47(5):1839–44.
Saw, Seang-Mei, et al. “A cohort study of incident myopia in Singaporean children.Invest Ophthalmol Vis Sci, vol. 47, no. 5, May 2006, pp. 1839–44. Pubmed, doi:10.1167/iovs.05-1081.
Saw S-M, Shankar A, Tan S-B, Taylor H, Tan DTH, Stone RA, Wong T-Y. A cohort study of incident myopia in Singaporean children. Invest Ophthalmol Vis Sci. 2006 May;47(5):1839–1844.

Published In

Invest Ophthalmol Vis Sci

DOI

ISSN

0146-0404

Publication Date

May 2006

Volume

47

Issue

5

Start / End Page

1839 / 1844

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Singapore
  • Risk Factors
  • Risk
  • Ophthalmology & Optometry
  • Myopia
  • Male
  • Intelligence Tests
  • Incidence
  • Humans