Dietary factors, myopia, and axial dimensions in children.

Journal Article (Journal Article)

PURPOSE: To evaluate the possible associations between dietary factors and myopia. DESIGN: Cross-sectional study. PARTICIPANTS: Eight hundred fifty-one Chinese schoolchildren from the Singapore Cohort Study of Risk Factors for Myopia. METHODS: Diet was assessed using a semiquantitative food-frequency questionnaire. Spherical equivalent (SE) refraction was assessed with an autorefractometer, and axial length (AL) by contact ultrasound A-scan biometry. MAIN OUTCOME MEASURES: Myopia was defined as SE< or =-0.5 diopters (D). Spherical equivalent and AL were analyzed by quartile groups. RESULTS: The mean age (+/-standard deviation) was 12.81+/-0.83 years, approximately half were male (422 children [49.6%]), and 653 (73.8%) children had myopia. In multivariate models, AL was longest in the highest quartile group of total cholesterol intake compared with the lowest (adjusted mean [95% confidence interval], 24.66 [24.62-24.71] mm vs. 24.32 [24.27-24.36] mm; P = 0.026, for trend) and was longest in the highest quartile group of saturated fat intake compared with the lowest (24.65 [24.60-24.70] vs. 24.36 [24.32-24.41] mm; P = 0.039, for trend). None of the nutrients was associated with SE or a diagnosis of myopia. CONCLUSIONS: Higher saturated fat and cholesterol intake are associated with longer AL in otherwise healthy Singapore Chinese schoolchildren.

Full Text

Duke Authors

Cited Authors

  • Lim, LS; Gazzard, G; Low, Y-L; Choo, R; Tan, DTH; Tong, L; Yin Wong, T; Saw, S-M

Published Date

  • May 2010

Published In

Volume / Issue

  • 117 / 5

Start / End Page

  • 993 - 997.e4

PubMed ID

  • 20079928

Electronic International Standard Serial Number (EISSN)

  • 1549-4713

Digital Object Identifier (DOI)

  • 10.1016/j.ophtha.2009.10.003


  • eng

Conference Location

  • United States