Reliability of different image analysis methods for scanning laser Doppler flowmetry.


Journal Article

PURPOSE: To assess reliability and reproducibility of different analysis methods for retinal capillary flow, volume, and velocity from scanning laser Doppler flowmetry (SLDF) topography. MATERIAL AND METHODS: SLDF topography analysis using the default retinal flowmeter (HRF) were compared to that using automatic full-field perfusion image analyzer (AFFPIA) and quantified as intraclass correlation coefficients (ICC). RESULTS: The AFFPIA full-field method had the highest reliability, with ICC 0.99 for capillary flow. The reproducibility using the AFFPIA full-field method was high ICC 0.74 for capillary flow. CONCLUSIONS: The AFFPIA full-field method is highly reliable and superior to the default HRF software.

Full Text

Duke Authors

Cited Authors

  • Kreis, AJ; Nguyen, T; Rogers, S; Wang, JJ; Harazny, J; Michelson, G; Farouque, HMO; Wong, TY

Published Date

  • May 2008

Published In

Volume / Issue

  • 33 / 5

Start / End Page

  • 493 - 499

PubMed ID

  • 18568887

Pubmed Central ID

  • 18568887

Electronic International Standard Serial Number (EISSN)

  • 1460-2202

Digital Object Identifier (DOI)

  • 10.1080/02713680802069149


  • eng

Conference Location

  • England