Skip to main content
Journal cover image

Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study.

Publication ,  Journal Article
Kawasaki, R; Wang, JJ; Aung, T; Tan, DTH; Mitchell, P; Sandar, M; Saw, S-M; Wong, TY; Singapore Malay Eye Study Group,
Published in: Ophthalmology
October 2008

OBJECTIVE: To describe the prevalence of age-related macular degeneration (AMD) in an Asian Malay population. DESIGN: Population-based cross-sectional study. PARTICIPANTS: An age-stratified random sample of Malay persons aged 40 to 80 years living in Singapore. METHODS: Participants were invited to a central clinic for a comprehensive examination. MAIN OUTCOME MEASURES: Early and late AMD signs were graded from retinal photographs following the Wisconsin grading system. RESULTS: Of 3280 participants who participated (78.7% response rate), 3265 had photographs of sufficient quality for grading of AMD signs. Early and late AMD were present in 160 (4.9%) and 23 (0.70%) participants, respectively. After age standardization, the prevalence of early AMD in Malay persons aged 40 to 80 years was estimated to be 3.5% (95% confidence interval [CI], 2.9%-4.1%) and that of late AMD was 0.34% (95% CI, 0.20%-0.49%). Early AMD was more prevalent in men than in women (6.1% vs. 3.8%); this was significant despite adjusting for age and smoking (odds ratio [OR], 1.56; 95% CI, 1.11-2.20). Late AMD also was more prevalent in men than in women (1.0% vs. 0.4%), although this was not statistically significant after adjusting for age and smoking (OR, 1.39; 95% CI, 0.52-3.68). The prevalence of early and late AMD was similar to that reported in the Blue Mountains Eye Study among white persons. CONCLUSIONS: The prevalence of AMD in Asian Malay people is similar to that in white persons from the Blue Mountains Eye Study. Early AMD signs were more frequent in men compared with women, an association that was not fully explained by the higher smoking rates in men.

Duke Scholars

Published In

Ophthalmology

DOI

EISSN

1549-4713

Publication Date

October 2008

Volume

115

Issue

10

Start / End Page

1735 / 1741

Location

United States

Related Subject Headings

  • Visual Acuity
  • Singapore
  • Prevalence
  • Photography
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Macular Degeneration
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kawasaki, R., Wang, J. J., Aung, T., Tan, D. T. H., Mitchell, P., Sandar, M., … Singapore Malay Eye Study Group, . (2008). Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study. Ophthalmology, 115(10), 1735–1741. https://doi.org/10.1016/j.ophtha.2008.02.012
Kawasaki, Ryo, Jie Jin Wang, Tin Aung, Donald T. H. Tan, Paul Mitchell, Mya Sandar, Seang-Mei Saw, Tien Y. Wong, and Tien Y. Singapore Malay Eye Study Group. “Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study.Ophthalmology 115, no. 10 (October 2008): 1735–41. https://doi.org/10.1016/j.ophtha.2008.02.012.
Kawasaki R, Wang JJ, Aung T, Tan DTH, Mitchell P, Sandar M, et al. Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study. Ophthalmology. 2008 Oct;115(10):1735–41.
Kawasaki, Ryo, et al. “Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study.Ophthalmology, vol. 115, no. 10, Oct. 2008, pp. 1735–41. Pubmed, doi:10.1016/j.ophtha.2008.02.012.
Kawasaki R, Wang JJ, Aung T, Tan DTH, Mitchell P, Sandar M, Saw S-M, Wong TY, Singapore Malay Eye Study Group. Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study. Ophthalmology. 2008 Oct;115(10):1735–1741.
Journal cover image

Published In

Ophthalmology

DOI

EISSN

1549-4713

Publication Date

October 2008

Volume

115

Issue

10

Start / End Page

1735 / 1741

Location

United States

Related Subject Headings

  • Visual Acuity
  • Singapore
  • Prevalence
  • Photography
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Macular Degeneration
  • Humans
  • Female