Medication use and retinal vessel diameters.

Journal Article

PURPOSE: To study the influence of different medications on retinal vessel diameters. DESIGN: Cross-sectional study. METHODS: Retinal photographs in the Beaver Dam Eye Study (n = 4926, aged 43 to 84 years) were digitized, and the diameters of retinal vessels were measured. Participants' current medications were recorded at the examination. RESULTS: There were few significant associations between medication use and retinal vessel diameters. After adjusting for age, blood pressure, and other factors, participants who were using topical beta-blocker eyedrops had narrower retinal arteriolar (P = .05) and venular (P = .006) diameters than nonusers. Systemic beta-blocker was not associated with retinal vessel diameter size. CONCLUSION: We found few associations between current medication use and retinal vessel diameter. Retinal vessels were narrowed in those taking antiglaucoma medications, most strikingly in those prescribed topical beta-blockers, although such a relationship could not be established among those using systemic beta-blockers.

Full Text

Duke Authors

Cited Authors

  • Wong, TY; Knudtson, MD; Klein, BEK; Klein, R; Hubbard, LD

Published Date

  • February 2005

Published In

Volume / Issue

  • 139 / 2

Start / End Page

  • 373 - 375

PubMed ID

  • 15734013

Pubmed Central ID

  • 15734013

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/j.ajo.2004.08.008


  • eng

Conference Location

  • United States