Impact of Diabetes Mellitus on Head and Neck Cancer Patients Undergoing Surgery.
Journal Article (Multicenter Study;Journal Article)
Objective
The impact of diabetes mellitus (DM) on surgical outcomes and cost of care for patients undergoing surgery for head and neck cancer (HNCA) is not well established. We used the Nationwide Inpatient Sample to analyze the postoperative impact of DM on HNCA patients.Study design
Population-based inpatient registry analysis.Setting
Academic medical center.Subjects and methods
Discharge data from the Nationwide Inpatient Sample were analyzed for patients undergoing HNCA surgery from 2002 to 2010. Patient demographics, comorbidities, length of stay, hospital charges, and postoperative complications were compared between HNCA patients with and without DM.Results
Of 31,075 patients, 4029 patients (13.0%) had a DM diagnosis. DM patients were older (65.7 ± 10.8 vs 61.1 ± 14.1 years old; P < .001), had more preexisting comorbidities, had longer hospitalizations, and incurred greater hospital charges. Compared with the non-DM cohort, DM patients experienced significantly higher rates of postoperative infections (2.6% vs 2.1%, P = .025), cardiac events (9.0% vs 4.3%, P < .001), pulmonary edema/failure (6.6% vs 5.7%, P = .023), acute renal failure (3.3% vs 1.5%, P < .001), and urinary tract infections (2.8 % vs 2.1%, P = .005). No differences in surgical wound healing rates were observed (0.1 vs 0.1, P = .794). On multivariate logistic regression corrected for age and race, DM patients had greater odds of postoperative infections (1.382, P = .007), cardiac events (1.893, P < .001), and acute renal failure (2.023, P < .001).Conclusions
DM is associated with greater length of stay and hospital charges among HNCA patients. DM patients have significantly greater rates of postoperative complications, including postoperative infections, cardiac events, and acute renal failure.Full Text
Duke Authors
Cited Authors
- Raikundalia, MD; Fang, CH; Spinazzi, EF; Vazquez, A; Park, RC; Baredes, S; Eloy, JA
Published Date
- February 2016
Published In
Volume / Issue
- 154 / 2
Start / End Page
- 294 - 299
PubMed ID
- 26443478
Pubmed Central ID
- 26443478
Electronic International Standard Serial Number (EISSN)
- 1097-6817
International Standard Serial Number (ISSN)
- 0194-5998
Digital Object Identifier (DOI)
- 10.1177/0194599815607852
Language
- eng