Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021.

Journal Article (Journal Article)

Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than females. Of 11 biomarkers assessed by sex and HIV-status, HIV-infected males had increased levels of soluble CD14 which inversely correlated with bone mineral content and bone mineral density measures, suggesting macrophage activation as a possible mechanism of differential bone loss.

Full Text

Duke Authors

Cited Authors

  • Ruan, A; Tobin, NH; Mulligan, K; Rollie, A; Li, F; Sleasman, J; Aldrovandi, GM

Published Date

  • August 1, 2016

Published In

Volume / Issue

  • 72 / 4

Start / End Page

  • 372 - 375

PubMed ID

  • 26885808

Pubmed Central ID

  • PMC4925249

Electronic International Standard Serial Number (EISSN)

  • 1944-7884

Digital Object Identifier (DOI)

  • 10.1097/QAI.0000000000000953


  • eng

Conference Location

  • United States