Chest Wall Deformity in the Radiation Oncology Clinic.


Journal Article

To determine the incidence of pectus excavatum (PE) and define anatomical chest wall metrics predictive of elevated mean heart dose (MHD) in patients with left-sided breast cancer receiving adjuvant radiotherapy.We reviewed 273 consecutively simulated patients from 1/2013-12/2014. Physical examination identified patients with clinically identifiable PE. Characteristics were compared between patients with and those without PE. Predictors of MHD were evaluated using linear regression.The average MHD for the entire cohort was 172 cGy. Of 273 patients, 10 (3.7%) were found to have clinically significant PE. Increase in the Haller Index was correlated with higher MHD (p<0.001). Through the use of individually optimized patient positioning and respiratory gating, MHD was not statistically different in patients with PE compared to those without (p=0.093).Although PE deformity is associated with unfavorable geometry in patients undergoing left-sided breast irradiation, carefully selected treatment technique can maintain acceptable MHD.

Full Text

Cited Authors

  • Stahl, JM; Hong, JC; Lester-Coll, NH; Kann, BH; Wilson, LD; Higgins, SA; Evans, SB

Published Date

  • October 2016

Published In

Volume / Issue

  • 36 / 10

Start / End Page

  • 5295 - 5300

PubMed ID

  • 27798891

Pubmed Central ID

  • 27798891

Electronic International Standard Serial Number (EISSN)

  • 1791-7530

International Standard Serial Number (ISSN)

  • 0250-7005

Digital Object Identifier (DOI)

  • 10.21873/anticanres.11101


  • eng