The Impact of Lens Vault on Visual Acuity and Refractive Error: Implications for Management of Primary Angle-closure Glaucoma.

Journal Article (Journal Article)

PURPOSE: To investigate the relationship between lens vault (LV), visual acuity (VA), and refraction. METHODS: This was a cross-sectional study of 2047 subjects aged 50 years and older recruited from a community polyclinic. Anterior segment optical coherence tomography was performed, and customized software was used to measure LV. VA was measured using a logarithm of minimum angle of resolution chart (logMAR chart; Lighthouse Inc.), and was classified as normal (logMAR<0.3), mild impairment (0.3<0.6), and moderate/severe impairment (logMAR>0.6). Refraction was measured with an autorefractor machine and spherical equivalent was defined as sphere plus half cylinder. Angle closure was defined as posterior trabecular meshwork not visible for ≥2 quadrants on nonindentation gonioscopy. RESULTS: Complete data were available for 1372 subjects including 295 (21.5%) with angle closure. Angle-closure subjects were significantly older (P<0.001), with shorter axial length (P<0.001), shallower anterior chamber depth (P<0.001), and greater LV (P<0.001). There was no significant difference in VA (P=0.12) compared with those without angle closure. After adjusting for age, sex, axial length, anterior chamber depth, and spherical equivalent, there was no significant association between LV and VA (P=0.35) or between LV and spherical equivalent (P=0.06). CONCLUSIONS: The magnitude of LV was not associated with VA or spherical equivalent. Lens extraction may be a consideration in eyes with angle closure with large LV in the absence of visually significant cataract.

Full Text

Duke Authors

Cited Authors

  • Nongpiur, ME; Singhal, S; Stewart, S; Htoon, HM; Narayanaswamy, AK; Wong, TY; Perera, SA; Aung, T

Published Date

  • March 2016

Published In

Volume / Issue

  • 25 / 3

Start / End Page

  • e236 - e240

PubMed ID

  • 25943738

Electronic International Standard Serial Number (EISSN)

  • 1536-481X

Digital Object Identifier (DOI)

  • 10.1097/IJG.0000000000000264


  • eng

Conference Location

  • United States