Family health history: an essential starting point for personalized risk assessment and disease prevention.

Journal Article (Journal Article)

Family health history (FHH) information is well established as a basis for assessing a patient's personal disease risk, but is underutilized for diagnosis and making medical recommendations. Epidemiological and genetic information have heightened the value of FHH to an individual's health. This has motivated the development of new FHH collection tools and strategies for family members, but will require greater awareness and knowledge by both patients and practitioners. FHH will be increasingly important as genomic data become a mainstay of medical diagnostics, since in many cases, a medically important FHH results from lineage-specific genetic variants. The impact of complementary FHH and genomic information will drive the pursuit of personalized and precise targeting of treatments and interventions aimed at maintaining patient health.

Full Text

Duke Authors

Cited Authors

  • Henrich, VC; Orlando, LA

Published Date

  • September 2016

Published In

Volume / Issue

  • 13 / 5

Start / End Page

  • 499 - 510

PubMed ID

  • 29767594

Electronic International Standard Serial Number (EISSN)

  • 1744-828X

Digital Object Identifier (DOI)

  • 10.2217/pme-2016-0007

Language

  • eng

Conference Location

  • England