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Is epigenetic inheritance a counterexample to the central dogma?

Publication ,  Conference
Rosenberg, A
Published in: History and philosophy of the life sciences
January 2006

This paper argues that nothing that has been discovered in the increasingly complex delails of gene regulation has provided any grounds to retract or qualify Crick's version of the central dogma. In particular it defends the role of the genes as the sole bearers of information, and argues that the mechanism of epigenetic modification of the DNA is but another vindication of Crick's version of the central dogma. The paper shows that arguments of C.K. Waters for the distinctive causual role of the genes are equivalent in important respects to the present ones and concludes with a defense of the informational role of the genes against an argument from trans-acting genetic regulation due to Stotz.

Duke Scholars

Published In

History and philosophy of the life sciences

EISSN

1742-6316

ISSN

0391-9714

Publication Date

January 2006

Volume

28

Issue

4

Start / End Page

549 / 565

Related Subject Headings

  • Science Studies
  • Promoter Regions, Genetic
  • Mutation
  • Molecular Biology
  • Models, Genetic
  • Humans
  • Genetic Variation
  • Gene Expression Profiling
  • Epigenesis, Genetic
  • Dissent and Disputes
 

Citation

APA
Chicago
ICMJE
MLA
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Rosenberg, A. (2006). Is epigenetic inheritance a counterexample to the central dogma? In History and philosophy of the life sciences (Vol. 28, pp. 549–565).
Rosenberg, Alex. “Is epigenetic inheritance a counterexample to the central dogma?” In History and Philosophy of the Life Sciences, 28:549–65, 2006.
Rosenberg A. Is epigenetic inheritance a counterexample to the central dogma? In: History and philosophy of the life sciences. 2006. p. 549–65.
Rosenberg, Alex. “Is epigenetic inheritance a counterexample to the central dogma?History and Philosophy of the Life Sciences, vol. 28, no. 4, 2006, pp. 549–65.
Rosenberg A. Is epigenetic inheritance a counterexample to the central dogma? History and philosophy of the life sciences. 2006. p. 549–565.
Journal cover image

Published In

History and philosophy of the life sciences

EISSN

1742-6316

ISSN

0391-9714

Publication Date

January 2006

Volume

28

Issue

4

Start / End Page

549 / 565

Related Subject Headings

  • Science Studies
  • Promoter Regions, Genetic
  • Mutation
  • Molecular Biology
  • Models, Genetic
  • Humans
  • Genetic Variation
  • Gene Expression Profiling
  • Epigenesis, Genetic
  • Dissent and Disputes