Is epigenetic inheritance a counterexample to the central dogma?

Conference Paper

This paper argues that nothing that has been discovered in the increasingly complex delails of gene regulation has provided any grounds to retract or qualify Crick's version of the central dogma. In particular it defends the role of the genes as the sole bearers of information, and argues that the mechanism of epigenetic modification of the DNA is but another vindication of Crick's version of the central dogma. The paper shows that arguments of C.K. Waters for the distinctive causual role of the genes are equivalent in important respects to the present ones and concludes with a defense of the informational role of the genes against an argument from trans-acting genetic regulation due to Stotz.

Duke Authors

Cited Authors

  • Rosenberg, A

Published Date

  • January 2006

Published In

Volume / Issue

  • 28 / 4

Start / End Page

  • 549 - 565

PubMed ID

  • 18351052

Electronic International Standard Serial Number (EISSN)

  • 1742-6316

International Standard Serial Number (ISSN)

  • 0391-9714