Pharmacogenetic challenges for the health care system.

Journal Article (Journal Article)

Pharmacogenetics--the effect of genotype on drug response--holds the promise of safer and more effective drug therapy. Genetic tests would be routinely given to patients prior to prescription of a drug, with therapeutic decisions based on the patient's drug-response profile. This paper examines the operational changes and the ethical, legal, and policy challenges that pharmacogenetic medicine poses for key actors in the health care system. Adaptation by drug companies, regulatory agencies, physicians, patients, insurers, and public funding agencies will be necessary to integrate pharmacogenetic medicine into health care.

Full Text

Duke Authors

Cited Authors

  • Robertson, JA; Brody, B; Buchanan, A; Kahn, J; McPherson, E

Published Date

  • July 2002

Published In

Volume / Issue

  • 21 / 4

Start / End Page

  • 155 - 167

PubMed ID

  • 12117126

Electronic International Standard Serial Number (EISSN)

  • 1544-5208

International Standard Serial Number (ISSN)

  • 0278-2715

Digital Object Identifier (DOI)

  • 10.1377/hlthaff.21.4.155


  • eng