Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries.
Publication
, Journal Article
Mwila, K; Chilengi, R; Simuyandi, M; Permar, SR; Becker-Dreps, S
Published in: Clin Vaccine Immunol
January 2017
The role of maternal immunity, received by infants either transplacentally or orally from breast milk, in rotavirus vaccine (RV) performance is evaluated here. Breastfeeding withholding has no effect on vaccine responses, but higher levels of transplacental rotavirus-specific IgG antibody contribute to reduced vaccine seroconversion. The gaps in knowledge on the factors associated with low RV efficacy in low- and middle-income countries (LMIC) remain, and further research is needed to shed more light on these issues.
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Published In
Clin Vaccine Immunol
DOI
EISSN
1556-679X
Publication Date
January 2017
Volume
24
Issue
1
Location
United States
Related Subject Headings
- Treatment Outcome
- Rotavirus Vaccines
- Rotavirus Infections
- Microbiology
- Immunology
- Immunoglobulin G
- Immunity, Maternally-Acquired
- Humans
- Developing Countries
- Antibodies, Viral
Citation
APA
Chicago
ICMJE
MLA
NLM
Mwila, K., Chilengi, R., Simuyandi, M., Permar, S. R., & Becker-Dreps, S. (2017). Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries. Clin Vaccine Immunol, 24(1). https://doi.org/10.1128/CVI.00405-16
Mwila, Katayi, Roma Chilengi, Michelo Simuyandi, Sallie R. Permar, and Sylvia Becker-Dreps. “Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries.” Clin Vaccine Immunol 24, no. 1 (January 2017). https://doi.org/10.1128/CVI.00405-16.
Mwila K, Chilengi R, Simuyandi M, Permar SR, Becker-Dreps S. Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries. Clin Vaccine Immunol. 2017 Jan;24(1).
Mwila, Katayi, et al. “Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries.” Clin Vaccine Immunol, vol. 24, no. 1, Jan. 2017. Pubmed, doi:10.1128/CVI.00405-16.
Mwila K, Chilengi R, Simuyandi M, Permar SR, Becker-Dreps S. Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries. Clin Vaccine Immunol. 2017 Jan;24(1).
Published In
Clin Vaccine Immunol
DOI
EISSN
1556-679X
Publication Date
January 2017
Volume
24
Issue
1
Location
United States
Related Subject Headings
- Treatment Outcome
- Rotavirus Vaccines
- Rotavirus Infections
- Microbiology
- Immunology
- Immunoglobulin G
- Immunity, Maternally-Acquired
- Humans
- Developing Countries
- Antibodies, Viral