Patient-reported upper extremity outcome measures used in breast cancer survivors: a systematic review.

Published

Journal Article (Review)

(1) To identify English-language published patient-reported upper extremity outcome measures used in breast cancer research and (2) to examine construct validity and responsiveness in patient-reported upper extremity outcome measures used in breast cancer research.PubMed, Cumulative Index to Nursing and Allied Health Literature, and ProQuest MEDLINE databases were searched up to February 5, 2013.Studies were included if a patient-reported upper extremity outcome measure was administered, the participants were diagnosed with breast cancer, and the study was published in English.A total of 865 articles were screened. Fifty-nine full text articles were assessed for eligibility. A total of 46 articles met the initial eligibility criteria for aim 1. Eleven of these articles reported means and SDs for the outcome scores and included a comparison group analysis for aim 2.Construct validity was evaluated by calculating effect sizes for known-group differences in 6 studies using the Disabilities of Arm, Shoulder and Hand (DASH), University of Pennsylvania Shoulder Score, Shoulder Disability Questionnaire-Dutch, and 10 Questions by Wingate. Responsiveness was analyzed comparing a treatment and control group by calculating the coefficient of responsiveness in 5 studies for the DASH and 10 Questions by Wingate.Eight different patient-reported upper extremity outcome measures have been reported in the peer-review literature for women with breast cancer; some that were specifically developed for breast cancer survivors (n=3) and others that were not (n=5). Based on the current evidence, we recommend administering the DASH to assess patient-reported upper extremity function in breast cancer survivors because the DASH has the most consistently large effects sizes for construct validity and responsiveness. Future large studies are needed for more definitive recommendations.

Full Text

Duke Authors

Cited Authors

  • Harrington, S; Michener, LA; Kendig, T; Miale, S; George, SZ

Published Date

  • January 2014

Published In

Volume / Issue

  • 95 / 1

Start / End Page

  • 153 - 162

PubMed ID

  • 23932969

Pubmed Central ID

  • 23932969

Electronic International Standard Serial Number (EISSN)

  • 1532-821X

International Standard Serial Number (ISSN)

  • 0003-9993

Digital Object Identifier (DOI)

  • 10.1016/j.apmr.2013.07.022

Language

  • eng