Lipoprotein response to exercise training and a low-fat diet in older subjects with glucose intolerance.

Journal Article (Journal Article)

The purpose of this study was to determine the effect of aerobic exercise training (Ex), a low-fat diet (LF, 19% fat), or combined interventions (LF-Ex) on lipoprotein cholesterol (LDL, HDL, and VLDL) and triglyceride (TG) concentrations in glucose-intolerant subjects while their weight was maintained. Baseline dietary fat and carbohydrate composition, body composition, body mass index, age, and lipoprotein cholesterol were not different among groups. Aerobic capacity increased in both exercise groups (P < 0.01) and remained unchanged in the LF group. Body composition was unaltered and change in body weight (kg) was small: Ex, -0.8 +/- 0.4, (P < 0.05); LF, +0.4 +/- 0.4; (NS); LF-Ex, -1.4 +/- 0.4 (P < 0.01). Exercise alone did not significantly affect lipoprotein cholesterol or TG concentrations. In LF and LF-Ex, respectively, decreases (P < 0.02) in total cholesterol (-0.66 +/- 0.24 and -0.42 +/- 0.21 mmol/L), HDL (-0.14 +/- 0.07 and -0.26 +/- 0.04), and LDL (-0.60 +/- 0.25 and -0.23 +/- 0.13) were seen after 12 wk, whereas VLDL and TG remained unchanged. Our data indicate that beneficial effects of exercise training on lipid indexes are not observed in subjects with impaired glucose tolerance on either an average US diet or a low-fat diet if substantial changes in weight or body composition do not occur.

Full Text

Duke Authors

Cited Authors

  • Hughes, VA; Fiatarone, MA; Ferrara, CM; McNamara, JR; Charnley, JM; Evans, WJ

Published Date

  • April 1994

Published In

Volume / Issue

  • 59 / 4

Start / End Page

  • 820 - 826

PubMed ID

  • 8147325

International Standard Serial Number (ISSN)

  • 0002-9165

Digital Object Identifier (DOI)

  • 10.1093/ajcn/59.4.820


  • eng

Conference Location

  • United States