High-intensity strength training in nonagenarians. Effects on skeletal muscle.

Journal Article (Journal Article)

Muscle dysfunction and associated mobility impairment, common among the frail elderly, increase the risk of falls, fractures, and functional dependency. We sought to characterize the muscle weakness of the very old and its reversibility through strength training. Ten frail, institutionalized volunteers aged 90 +/- 1 years undertook 8 weeks of high-intensity resistance training. Initially, quadriceps strength was correlated negatively with walking time (r = -.745). Fat-free mass (r = .732) and regional muscle mass (r = .752) were correlated positively with muscle strength. Strength gains averaged 174% +/- 31% (mean +/- SEM) in the 9 subjects who completed training. Midthigh muscle area increased 9.0% +/- 4.5%. Mean tandem gait speed improved 48% after training. We conclude that high-resistance weight training leads to significant gains in muscle strength, size, and functional mobility among frail residents of nursing homes up to 96 years of age.

Full Text

Duke Authors

Cited Authors

  • Fiatarone, MA; Marks, EC; Ryan, ND; Meredith, CN; Lipsitz, LA; Evans, WJ

Published Date

  • June 13, 1990

Published In

Volume / Issue

  • 263 / 22

Start / End Page

  • 3029 - 3034

PubMed ID

  • 2342214

International Standard Serial Number (ISSN)

  • 0098-7484


  • eng

Conference Location

  • United States