Suppression of ghost artifacts arising from long T1
species in segmented inversion-recovery imaging.
We demonstrate an improved segmented inversion-recovery sequence that suppresses ghost artifacts arising from tissues with long T1
( > 1.5 s).
Theory and methods
species such as pericardial fluid can create bright ghost artifacts in segmented, inversion-recovery MRI because of oscillations in longitudinal magnetization between segments. A single dummy acquisition at the beginning of the sequence can reduce oscillations; however, its effectiveness in suppressing long T1
artifacts is unknown. In this study, we systematically evaluated several test sequences, including a prototype (saturation post-pulse readout to eliminate spurious signal: SPPRESS) in simulations, phantoms, and patients.
SPPRESS reduced artifact signal 90% ± 25% and 74% ± 28% compared with Control and Single-Dummy methods in phantoms. SPPRESS performed well at 1.5 Tesla (T) and 3T, with steady-state free precession (SSFP) and fast low-angle shot (FLASH) readout, with conventional and phase-sensitive reconstruction, and over a range of physiologic heart rates. A review of 100 consecutive clinical cardiac MRI scans revealed large fluid collections (eg, regions with long T1
) in 14% of patients. In a prospectively enrolled cohort of 16 patients with visible long T1
fluids, SPPRESS appreciably reduced artifacts in all cases compared with Control and Single-Dummy methods.
We developed and validated a new robust method, SPPRESS, for reducing artifacts due to long T1
species across a wide range of imaging and physiologic conditions. Magn Reson Med 78:1442-1451, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
Jenista, ER; Rehwald, WG; Chaptini, NH; Kim, HW; Parker, MA; Wendell, DC; Chen, E-L; Kim, RJ
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