Suppression of ghost artifacts arising from long T1 species in segmented inversion-recovery imaging.

Journal Article (Journal Article)

PURPOSE: We demonstrate an improved segmented inversion-recovery sequence that suppresses ghost artifacts arising from tissues with long T1 ( > 1.5 s). THEORY AND METHODS: Long T1 species such as pericardial fluid can create bright ghost artifacts in segmented, inversion-recovery MRI because of oscillations in longitudinal magnetization between segments. A single dummy acquisition at the beginning of the sequence can reduce oscillations; however, its effectiveness in suppressing long T1 artifacts is unknown. In this study, we systematically evaluated several test sequences, including a prototype (saturation post-pulse readout to eliminate spurious signal: SPPRESS) in simulations, phantoms, and patients. RESULTS: SPPRESS reduced artifact signal 90% ± 25% and 74% ± 28% compared with Control and Single-Dummy methods in phantoms. SPPRESS performed well at 1.5 Tesla (T) and 3T, with steady-state free precession (SSFP) and fast low-angle shot (FLASH) readout, with conventional and phase-sensitive reconstruction, and over a range of physiologic heart rates. A review of 100 consecutive clinical cardiac MRI scans revealed large fluid collections (eg, regions with long T1 ) in 14% of patients. In a prospectively enrolled cohort of 16 patients with visible long T1 fluids, SPPRESS appreciably reduced artifacts in all cases compared with Control and Single-Dummy methods. CONCLUSION: We developed and validated a new robust method, SPPRESS, for reducing artifacts due to long T1 species across a wide range of imaging and physiologic conditions. Magn Reson Med 78:1442-1451, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Full Text

Duke Authors

Cited Authors

  • Jenista, ER; Rehwald, WG; Chaptini, NH; Kim, HW; Parker, MA; Wendell, DC; Chen, E-L; Kim, RJ

Published Date

  • October 2017

Published In

Volume / Issue

  • 78 / 4

Start / End Page

  • 1442 - 1451

PubMed ID

  • 27868238

Pubmed Central ID

  • PMC6696919

Electronic International Standard Serial Number (EISSN)

  • 1522-2594

Digital Object Identifier (DOI)

  • 10.1002/mrm.26554


  • eng

Conference Location

  • United States