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Hürthle cell carcinoma: current perspectives.

Publication ,  Journal Article
Ahmadi, S; Stang, M; Jiang, XS; Sosa, JA
Published in: Onco Targets Ther
2016

Hürthle cell carcinoma (HCC) can present either as a minimally invasive or as a widely invasive tumor. HCC generally has a more aggressive clinical behavior compared with the other differentiated thyroid cancers, and it is associated with a higher rate of distant metastases. Minimally invasive HCC demonstrates much less aggressive behavior; lesions <4 cm can be treated with thyroid lobectomy alone, and without radioactive iodine (RAI). HCC has been observed to be less iodine-avid compared with other differentiated thyroid cancers; however, recent data have demonstrated improved survival with RAI use in patients with HCC >2 cm and those with nodal and distant metastases. Patients with localized iodine-resistant disease who are not candidates for a wait-and-watch approach can be treated with localized therapies. Systemic therapy is reserved for patients with progressive, widely metastatic HCC.

Duke Scholars

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Published In

Onco Targets Ther

DOI

ISSN

1178-6930

Publication Date

2016

Volume

9

Start / End Page

6873 / 6884

Location

New Zealand

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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Chicago
ICMJE
MLA
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Ahmadi, S., Stang, M., Jiang, X. S., & Sosa, J. A. (2016). Hürthle cell carcinoma: current perspectives. Onco Targets Ther, 9, 6873–6884. https://doi.org/10.2147/OTT.S119980
Ahmadi, Sara, Michael Stang, Xiaoyin Sara Jiang, and Julie Ann Sosa. “Hürthle cell carcinoma: current perspectives.Onco Targets Ther 9 (2016): 6873–84. https://doi.org/10.2147/OTT.S119980.
Ahmadi S, Stang M, Jiang XS, Sosa JA. Hürthle cell carcinoma: current perspectives. Onco Targets Ther. 2016;9:6873–84.
Ahmadi, Sara, et al. “Hürthle cell carcinoma: current perspectives.Onco Targets Ther, vol. 9, 2016, pp. 6873–84. Pubmed, doi:10.2147/OTT.S119980.
Ahmadi S, Stang M, Jiang XS, Sosa JA. Hürthle cell carcinoma: current perspectives. Onco Targets Ther. 2016;9:6873–6884.

Published In

Onco Targets Ther

DOI

ISSN

1178-6930

Publication Date

2016

Volume

9

Start / End Page

6873 / 6884

Location

New Zealand

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis