Penicillin allergy: A practical guide for clinicians.

Journal Article (Journal Article;Review)

Penicillin allergy is the most commonly reported drug allergy in the United States. However, after undergoing a complete evaluation by a board-certified allergist, including skin testing, 90% of patients labeled as 'penicillin-allergic' are able to tolerate penicillin. Clinical presentation is key in classifying reactions as either mediated by or not mediated by immunoglobulin E (IgE), and in determining which patients may benefit from penicillin skin testing, graded-dose challenge, or desensitization. Cross-reactivity between penicillin and other beta-lactams is less common than previously thought.

Full Text

Duke Authors

Cited Authors

  • Gonzalez-Estrada, A; Radojicic, C

Published Date

  • May 2015

Published In

Volume / Issue

  • 82 / 5

Start / End Page

  • 295 - 300

PubMed ID

  • 25973877

Electronic International Standard Serial Number (EISSN)

  • 1939-2869

Digital Object Identifier (DOI)

  • 10.3949/ccjm.82a.14111


  • eng

Conference Location

  • United States