PHD Inhibition Mitigates and Protects Against Radiation-Induced Gastrointestinal Toxicity via HIF2
Journal Article
Pharmacologic inhibition or knockout of HIF-prolyl hydroxylases in mice reduces morbidity and mortality from radiation-induced gastrointestinal syndrome.
Full Text
Duke Authors
Cited Authors
- Taniguchi, CM; Miao, YR; Diep, AN; Wu, C; Rankin, EB; Atwood, TF; Xing, L; Giaccia, AJ
Published Date
- May 14, 2014
Published In
Volume / Issue
- 6 / 236
Published By
Electronic International Standard Serial Number (EISSN)
- 1946-6242
International Standard Serial Number (ISSN)
- 1946-6234
Digital Object Identifier (DOI)
- 10.1126/scitranslmed.3008523
Language
- en