Estimation of macular pigment optical density in the elderly: test-retest variability and effect of optical blur in pseudophakic subjects.
The reproducibility of macular pigment optical density (MPOD) estimates in the elderly was assessed in 40 subjects (age: 79.1+/-3.5). Test-retest variability was good (Pearson's r coefficient: 0.734), with an average coefficient of variation (CV) of 18.4% and an intraclass correlation coefficient (ICC) of 0.96. The effect of optical blur on MPOD estimates was investigated in 22 elderly pseudophakic subjects (age: 79.9+/-3.6) by comparing the baseline MPOD, obtained with an optimal correction, with MPODs obtained with a +/-1.00-diopter optical blur. This optical blur did not cause differences in the MPOD estimates, its accuracy, or test duration.
Gallaher, KT; Mura, M; Todd, WA; Harris, TL; Kenyon, E; Harris, T; Johnson, KC; Satterfield, S; Kritchevsky, SB; Iannaccone, A; Health ABC Study,
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