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Reduction of cerebellar volume in major depression: A controlled MRI study

Publication ,  Journal Article
Escalona, PR; Early, B; McDonald, WM; Doraiswamy, PM; Shah, SA; Husain, MM; Boyko, OB; Figiel, GS; Ellinwood, EH; Nemeroff, CB; Krishnan, KRR
Published in: Depression
January 1, 1993

A systematic sampling stereological method of serially acquired axial intermediate T2‐weighted Spin echo magnetic resonance imaging (MRI) of the brain was used to measure cerebellar volume in 30 patients who fulfilled DSM III criteria for major depression and compared with 35 normal controls. The mean cerebellar volume of depressed patients was significantly smaller than the controls. This preliminary study adds new evidence for the possible participation of the cerebellum in the pathophysiology of major depression and warrants further investigation in this area. Depression 1:156–158 (1993). © 1993 Wiley‐Liss, Inc. Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company

Duke Scholars

Published In

Depression

DOI

EISSN

1522-7162

ISSN

1062-6417

Publication Date

January 1, 1993

Volume

1

Issue

3

Start / End Page

156 / 158
 

Citation

APA
Chicago
ICMJE
MLA
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Escalona, P. R., Early, B., McDonald, W. M., Doraiswamy, P. M., Shah, S. A., Husain, M. M., … Krishnan, K. R. R. (1993). Reduction of cerebellar volume in major depression: A controlled MRI study. Depression, 1(3), 156–158. https://doi.org/10.1002/depr.3050010307
Escalona, P. R., B. Early, W. M. McDonald, P. M. Doraiswamy, S. A. Shah, M. M. Husain, O. B. Boyko, et al. “Reduction of cerebellar volume in major depression: A controlled MRI study.” Depression 1, no. 3 (January 1, 1993): 156–58. https://doi.org/10.1002/depr.3050010307.
Escalona PR, Early B, McDonald WM, Doraiswamy PM, Shah SA, Husain MM, et al. Reduction of cerebellar volume in major depression: A controlled MRI study. Depression. 1993 Jan 1;1(3):156–8.
Escalona, P. R., et al. “Reduction of cerebellar volume in major depression: A controlled MRI study.” Depression, vol. 1, no. 3, Jan. 1993, pp. 156–58. Scopus, doi:10.1002/depr.3050010307.
Escalona PR, Early B, McDonald WM, Doraiswamy PM, Shah SA, Husain MM, Boyko OB, Figiel GS, Ellinwood EH, Nemeroff CB, Krishnan KRR. Reduction of cerebellar volume in major depression: A controlled MRI study. Depression. 1993 Jan 1;1(3):156–158.
Journal cover image

Published In

Depression

DOI

EISSN

1522-7162

ISSN

1062-6417

Publication Date

January 1, 1993

Volume

1

Issue

3

Start / End Page

156 / 158