High-speed photoacoustic microscopy of mouse cortical microhemodynamics.
Journal Article (Journal Article)
We applied high-speed photoacoustic microscopy (PAM) for both cortical microenvironment studies and dynamic brain studies, with micrometer-level optical resolution and a millisecond-level cross-sectional imaging speed over a millimeter-level field of view. We monitored blood flow redistribution in mini-stroke mouse models and cerebral autoregulation induced by a vasoactive agent. Our results collectively suggest that high-speed PAM is a promising tool for understanding dynamic neurophysiological phenomena, complementing conventional imaging modalities.
- Lin, L; Yao, J; Zhang, R; Chen, C-C; Huang, C-H; Li, Y; Wang, L; Chapman, W; Zou, J; Wang, LV
- June 2017
Volume / Issue
- 10 / 6-7
Start / End Page
- 792 - 798
Pubmed Central ID
Electronic International Standard Serial Number (EISSN)
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)