PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model.
Published
Journal Article
An initial evaluation of PEG-bHb was performed using a modified hypovolemic shock model. PEG-bHb had a substantially longer intravascular half-life than native Hb and no measurable hemoglobinuria was observed in the canine. PEG-bHb allowed successful resuscitation with an oxygen carrying capacity of 14-22% over that of lactated Ringer's solution.
Full Text
Duke Authors
Cited Authors
- Nho, K; Glower, D; Bredehoeft, S; Shankar, H; Shorr, R; Abuchowski, A
Published Date
- 1992
Published In
Volume / Issue
- 20 / 2-4
Start / End Page
- 511 - 524
PubMed ID
- 1391472
Pubmed Central ID
- 1391472
International Standard Serial Number (ISSN)
- 1055-7172
Language
- eng
Conference Location
- United States