Statistical analysis of genome-wide association studies for myopia
Genome wide association (GWA) studies have become a powerful approach for identifying genetic loci or susceptibility genes for common complex diseases.While the number of susceptibility loci identified by GWA studies is increasing, GWA studies for myopia are lagging behind many complex diseases. However, it is expected that more GWA studies related to myopia phenotypes will be reported in the near future. In this chapter, we describe the aspects of statistical analysis of the GWA study for myopia, including study design, quality control procedures, methods for association tests, and myopia related analysis issues.
- Myopia: Animal Models to Clinical Trials
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International Standard Book Number 10 (ISBN-10)
International Standard Book Number 13 (ISBN-13)
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