Statistical analysis of genome-wide association studies for myopia

Book Section

Genome wide association (GWA) studies have become a powerful approach for identifying genetic loci or susceptibility genes for common complex diseases.While the number of susceptibility loci identified by GWA studies is increasing, GWA studies for myopia are lagging behind many complex diseases. However, it is expected that more GWA studies related to myopia phenotypes will be reported in the near future. In this chapter, we describe the aspects of statistical analysis of the GWA study for myopia, including study design, quality control procedures, methods for association tests, and myopia related analysis issues.

Full Text

Duke Authors

Cited Authors

  • Li, YJ; Fan, Q

Published Date

  • January 1, 2010

Book Title

  • Myopia: Animal Models to Clinical Trials

Start / End Page

  • 244 - 267

International Standard Book Number 10 (ISBN-10)

  • 9812832971

International Standard Book Number 13 (ISBN-13)

  • 9789812832979

Digital Object Identifier (DOI)

  • 10.1142/9789812832986_0013

Citation Source

  • Scopus