Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia.
Publication
, Journal Article
Grover, SK; Srivastava, KK; Singh, VS; Misra, UK
Published in: Int J Vitam Nutr Res
1985
The hepatic drug metabolising enzymes activity has been studied in rats exposed to acute hypoxia alone or along with supplementation of single dose of 10 000 I.U. Vitamin A. Hypoxic stress reduces the activities of cytochrome P-450, cytochrome c-reductase and aniline hydroxylase. Administration of single dose of 10 000 I.U. of Vitamin A to the rats 12 h before hypoxia reverses the effect of hypoxia on these enzymes. Thus Vitamin A seems to play a protective role in rats exposed to hypoxia on the activity of MFO system.
Duke Scholars
Published In
Int J Vitam Nutr Res
ISSN
0300-9831
Publication Date
1985
Volume
55
Issue
4
Start / End Page
391 / 393
Location
Switzerland
Related Subject Headings
- Vitamin A
- Rats, Inbred Strains
- Rats
- Nutrition & Dietetics
- NADH Dehydrogenase
- Microsomes, Liver
- Male
- Kinetics
- Hypoxia
- Cytochrome P-450 Enzyme System
Citation
APA
Chicago
ICMJE
MLA
NLM
Grover, S. K., Srivastava, K. K., Singh, V. S., & Misra, U. K. (1985). Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia. Int J Vitam Nutr Res, 55(4), 391–393.
Grover, S. K., K. K. Srivastava, V. S. Singh, and U. K. Misra. “Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia.” Int J Vitam Nutr Res 55, no. 4 (1985): 391–93.
Grover SK, Srivastava KK, Singh VS, Misra UK. Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia. Int J Vitam Nutr Res. 1985;55(4):391–3.
Grover, S. K., et al. “Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia.” Int J Vitam Nutr Res, vol. 55, no. 4, 1985, pp. 391–93.
Grover SK, Srivastava KK, Singh VS, Misra UK. Effect of vitamin A on hepatic microsomal drug metabolising enzymes activity in rats exposed to acute hypoxia. Int J Vitam Nutr Res. 1985;55(4):391–393.
Published In
Int J Vitam Nutr Res
ISSN
0300-9831
Publication Date
1985
Volume
55
Issue
4
Start / End Page
391 / 393
Location
Switzerland
Related Subject Headings
- Vitamin A
- Rats, Inbred Strains
- Rats
- Nutrition & Dietetics
- NADH Dehydrogenase
- Microsomes, Liver
- Male
- Kinetics
- Hypoxia
- Cytochrome P-450 Enzyme System