Biochemical development of the rat lung: studies on cellular DNA, RNA and protein content in relation to maternal vitamin A status.

Journal Article

The effect of maternal vitamin A restriction on the biochemical development of the lung in rats has been studied. The vitamin A status of dams has been varied by supplying low, medium and adequate amounts of vitamin A (6, 40 and 100 micrograms retinol/day/kg body weight, respectively) during pregnancy and suckling. The results demonstrate that the restricted supply of vitamin A to the mother affected the growth and development of the lung in parameters of tissue weight, DNA and protein levels and their biosynthesis from respective labelled precursors, RNA contents, cell number and cell size.

Full Text

Duke Authors

Cited Authors

  • Sharma, HS; Misra, UK

Published Date

  • June 1, 1987

Published In

Volume / Issue

  • 26 / 2

Start / End Page

  • 116 - 124

PubMed ID

  • 2442894

International Standard Serial Number (ISSN)

  • 0044-264X

Digital Object Identifier (DOI)

  • 10.1007/bf02019607

Language

  • eng