Distribution of vitamin A in various organs of rats in relation to the quality and the quantity of dietary proteins.

Journal Article (Journal Article)

The influence of the quality and the quantity of dietary proteins on the distribution of a single massive dose of vitamin A in various organs of growing Wistar strain rats has been studied by using casein and bengal gram diets at 20% and 10% protein levels. The distribution of [3H]-retinyl acetate in various tissues was also investigated in these dietary conditions. The results show that the hepatic storage of dietary as well as a single massive dose (20,000 I.U.) of vitamin A was profoundly decreased in the rats fed on bengal gram diets as compared to those fed on casein diets. Regardless of hepatic stores, the plasma vitamin A levels were comparable in all the groups. Feeding of low quality of protein reduced the tissue distribution of [3H]-retinyl acetate in control as well as rats given a massive dose of vitamin A. This study suggests that both the poor quality and the inadequate quantity of dietary protein are detrimental influences on the vitamin A status of the growing rats.

Full Text

Duke Authors

Cited Authors

  • Sharma, HS; Misra, UK

Published Date

  • March 1, 1987

Published In

Volume / Issue

  • 26 / 1

Start / End Page

  • 43 - 51

PubMed ID

  • 3111110

International Standard Serial Number (ISSN)

  • 0044-264X

Digital Object Identifier (DOI)

  • 10.1007/BF02023818


  • eng

Conference Location

  • Germany