Placental transfer of metals of coal fly ash into various fetal organs of rat.

Journal Article (Journal Article)

Fly ash (100 mg/kg body weight) was administered intratracheally to 14-day pregnant rats for 6 consecutive days. On day 20 of gestation the translocation of metals present in the fly ash to various maternal and fetal organs was studied. Fly ash administration to pregnant mothers retarded the growth of fetal heart and kidney as determined by their weights. Fly ash instillation increased organ levels of nearly all the metals studied in both mother and fetus. Most of the metals present in coal fly ash were transferred in significant amounts through placenta to several fetal organs. However, the pattern of their distribution into various fetal organs was different for different metals.

Full Text

Duke Authors

Cited Authors

  • Srivastava, VK; Chauhan, SS; Srivastava, PK; Shukla, RR; Kumar, V; Misra, UK

Published Date

  • 1990

Published In

Volume / Issue

  • 64 / 2

Start / End Page

  • 153 - 156

PubMed ID

  • 2350235

International Standard Serial Number (ISSN)

  • 0340-5761

Digital Object Identifier (DOI)

  • 10.1007/BF01974402


  • eng

Conference Location

  • Germany