Interaction of ethanol, cholesterol and vitamin A on phospholipid methylation in hepatic microsomes of rats.

Journal Article (Journal Article)

Effect of ethanol, cholesterol and vitamin A either alone or in combination has been studied on cyt P450 and phospholipid methylation in hepatic microsomes of rats. Ethanol increased cyt P450 activity and decreased phospholipid methylation. Cholesterol effects were opposite to ethanol. Combination of cholesterol and ethanol decreased cyt P450 activity and increased phospholipid methylation. Vitamin A, which alone did not affect cyt P450 activity and phospholipid methylation behaved like cholesterol when given along with ethanol.

Full Text

Duke Authors

Cited Authors

  • Srivastava, R; Srivastava, N; Misra, UK

Published Date

  • 1990

Published In

Volume / Issue

  • 60 / 3

Start / End Page

  • 236 - 239

PubMed ID

  • 2276880

International Standard Serial Number (ISSN)

  • 0300-9831

Language

  • eng

Conference Location

  • Switzerland