Phosphoinositides of sheep platelets plasma membranes.

Published

Journal Article

Phospholipid composition of sheep blood platelets and its various plasma membrane fractions have been analyzed. Based on their flotation rates in discontinuous sucrose density gradient centrifugation, three membrane fractions were isolated. 5'-Nucelotidase and alkaline phosphatase were distributed nearly equally in all the three membrane fractions. However these membrane fractions showed differences in the distribution of phosphatidyl ethanolamine, phosphatidyl choline and phosphoinositides. Phosphatidyl ethanolamine was predominant in fraction I (11.05 micrograms PLP/mg protein) while phosphatidyl choline was predominant in fractions II and III (110.10 and 68.30 micrograms PLP/mg protein respectively). Phosphatidyl inositol (Ptd-InsP) was equally distributed in all three membrane fractions. However, both Ptd-InsP and phosphatidyl inositol 4,5-bisphosphate were about 4-fold higher in fraction II (73.55 and 89.89 micrograms PLP/mg protein respectively).

Full Text

Duke Authors

Cited Authors

  • Kumar, V; Srivastava, N; Grover, SK; Jaiswal, AS; Bansal, SK; Misra, UK

Published Date

  • April 1991

Published In

Volume / Issue

  • 28 / 2

Start / End Page

  • 133 - 135

PubMed ID

  • 1652550

Pubmed Central ID

  • 1652550

Electronic International Standard Serial Number (EISSN)

  • 0975-0959

International Standard Serial Number (ISSN)

  • 0301-1208

Language

  • eng