Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture).

Journal Article (Journal Article;Review)

DNA molecules are not completely stable, they are subject to chemical or photochemical damage and errors that occur during DNA replication resulting in mismatched base pairs. Through mechanistic studies Paul Modrich showed how replication errors are corrected by strand-directed mismatch repair in Escherichia coli and human cells.

Full Text

Duke Authors

Cited Authors

  • Modrich, P

Published Date

  • July 18, 2016

Published In

Volume / Issue

  • 55 / 30

Start / End Page

  • 8490 - 8501

PubMed ID

  • 27198632

Pubmed Central ID

  • PMC5193110

Electronic International Standard Serial Number (EISSN)

  • 1521-3773

Digital Object Identifier (DOI)

  • 10.1002/anie.201601412


  • eng

Conference Location

  • Germany