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Physical and psychological health in rare cancer survivors.

Publication ,  Journal Article
Horick, NK; Manful, A; Lowery, J; Domchek, S; Moorman, P; Griffin, C; Visvanathan, K; Isaacs, C; Kinney, AY; Finkelstein, DM
Published in: J Cancer Surviv
February 2017

PURPOSE: Registries provide a unique tool for tracking quality of life in rare cancer survivors, whose survivorship experience is less known than for common cancers. This paper reports on these outcomes in 321 patients enrolled in the Rare Cancer Genetics Registry diagnosed with rare gastrointestinal, genitourinary, gynecologic, sarcoma, head/neck, or hematologic cancers. METHODS: Four outcomes were assessed, reflecting registrants' self-reported physical and mental health, psychological distress, and loneliness. Combining all patients into a single analysis, regression was used to evaluate the association between outcomes and socio-demographic and clinical factors. RESULTS: Median time since diagnosis was 3 years (range 0-9); 69 % were no longer in treatment. Poorer physical health was reported in registrants who were older at diagnosis, unmarried, and still in treatment. Poorer mental status was associated with younger diagnosis age and unmarried status. Psychological distress varied by cancer type and was higher among currently treated and unmarried registrants. Greater loneliness was reported in registrants with gynecological cancers, and those who were less educated or unmarried. The physical and mental health profile of rare cancer survivors is similar to what is reported for common cancers. CONCLUSIONS: Unmarried participants reported poorer outcomes on all measures of quality of life. Furthermore, physical and mental health were not significantly different by cancer type after adjustment for diagnosis age, whether currently in treatment and marital status. Thus, the combined analysis performed here is a useful way to analyze outcomes in less common diseases. Our findings could be valuable in guiding evaluation and intervention for issues impacting quality of life. IMPLICATIONS FOR CANCER SURVIVORS: Rare cancer survivors, particularly those without spousal support, should be monitored for challenges to the physical as well as psychological aspects of quality of life.

Duke Scholars

Published In

J Cancer Surviv

DOI

EISSN

1932-2267

Publication Date

February 2017

Volume

11

Issue

1

Start / End Page

158 / 165

Location

United States

Related Subject Headings

  • Survivors
  • Survival Rate
  • Registries
  • Rare Diseases
  • Quality of Life
  • Oncology & Carcinogenesis
  • Neoplasms
  • Middle Aged
  • Mental Health
  • Male
 

Citation

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Horick, N. K., Manful, A., Lowery, J., Domchek, S., Moorman, P., Griffin, C., … Finkelstein, D. M. (2017). Physical and psychological health in rare cancer survivors. J Cancer Surviv, 11(1), 158–165. https://doi.org/10.1007/s11764-016-0573-0
Horick, Nora K., Adoma Manful, Jan Lowery, Susan Domchek, Patricia Moorman, Constance Griffin, Kala Visvanathan, Claudine Isaacs, Anita Y. Kinney, and Dianne M. Finkelstein. “Physical and psychological health in rare cancer survivors.J Cancer Surviv 11, no. 1 (February 2017): 158–65. https://doi.org/10.1007/s11764-016-0573-0.
Horick NK, Manful A, Lowery J, Domchek S, Moorman P, Griffin C, et al. Physical and psychological health in rare cancer survivors. J Cancer Surviv. 2017 Feb;11(1):158–65.
Horick, Nora K., et al. “Physical and psychological health in rare cancer survivors.J Cancer Surviv, vol. 11, no. 1, Feb. 2017, pp. 158–65. Pubmed, doi:10.1007/s11764-016-0573-0.
Horick NK, Manful A, Lowery J, Domchek S, Moorman P, Griffin C, Visvanathan K, Isaacs C, Kinney AY, Finkelstein DM. Physical and psychological health in rare cancer survivors. J Cancer Surviv. 2017 Feb;11(1):158–165.
Journal cover image

Published In

J Cancer Surviv

DOI

EISSN

1932-2267

Publication Date

February 2017

Volume

11

Issue

1

Start / End Page

158 / 165

Location

United States

Related Subject Headings

  • Survivors
  • Survival Rate
  • Registries
  • Rare Diseases
  • Quality of Life
  • Oncology & Carcinogenesis
  • Neoplasms
  • Middle Aged
  • Mental Health
  • Male