A Quality Improvement Project to Increase Early Detection of Syphilis Infection or Re-infection in HIV-infected Men Who Have Sex With Men.

Journal Article (Journal Article)

Our quality improvement project evaluated whether testing for syphilis every 3 to 6 months with routine HIV laboratory monitoring had an effect on early detection of asymptomatic syphilis infection/re-infection in HIV-infected men who have sex with men. Retrospective analysis of syphilis testing and infections in a sample of this population (N = 245) was conducted after establishing a change-of-practice quality improvement initiative in a not-for-profit, community-based, grant-funded clinic. We compared the clinic's annual rates of syphilis before and after intervention implementation. The detection rate was 6.6% in the preintervention practice change group and 15.5% in the postintervention group. Increased testing identified 27 syphilis cases that would not otherwise have been identified until the annual comprehensive examination. Increased testing frequency led to earlier detection of syphilis, which was clinically significant, showing a potential to decrease the number of new syphilis and HIV infections and to decrease health care expenditures.

Full Text

Duke Authors

Cited Authors

  • Cheeks, MA; Fransua, M; Stringer, HG; Silva, S; Relf, M

Published Date

  • March 2016

Published In

Volume / Issue

  • 27 / 2

Start / End Page

  • 143 - 152

PubMed ID

  • 26646978

Electronic International Standard Serial Number (EISSN)

  • 1552-6917

International Standard Serial Number (ISSN)

  • 1055-3290

Digital Object Identifier (DOI)

  • 10.1016/j.jana.2015.11.002


  • eng