Intestinal transplantation.

Journal Article (Journal Article;Review)

Intestinal transplantation has now emerged as a lifesaving therapeutic option and standard of care for patients with irreversible intestinal failure. Improvement in survival over the years has justified expansion of the indications for intestinal transplantation beyond the original indications approved by Center for Medicare and Medicaid services. Management of patients with intestinal failure is complex and requires a multidisciplinary approach to accurately select candidates who would benefit from rehabilitation versus transplantation. Significant strides have been made in patient and graft survival with several advancements in the perioperative management through timely referral, improved patient selection, refinement in the surgical techniques and better understanding of the immunopathology of intestinal transplantation. The therapeutic efficacy of the procedure is well evident from continuous improvements in functional status, quality of life and cost-effectiveness of the procedure. This current review summarizes various aspects including current practices and evidence based recommendations of intestinal transplantation.

Full Text

Duke Authors

Cited Authors

  • Rege, A; Sudan, D

Published Date

  • April 2016

Published In

Volume / Issue

  • 30 / 2

Start / End Page

  • 319 - 335

PubMed ID

  • 27086894

Electronic International Standard Serial Number (EISSN)

  • 1532-1916

Digital Object Identifier (DOI)

  • 10.1016/j.bpg.2016.02.010


  • eng

Conference Location

  • Netherlands