Review article: Anaphylactic reactions during cardiac surgery
Anaphylactic reactions during cardiac surgery may present as acute cardiopulmonary dysfunction and require prompt and aggressive therapy. Recognition, with appropriate therapeutic intervention, is essential to prevent the life-threatening complications associated with perioperative anaphylaxis. Clinically, the life-threatening reactions to protamine seen following CPB appear to represent anaphylaxis-mediated events due to IgE, IgG and complement activation. © 1991, Sage Publications. All rights reserved.
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