Differential changes in plasma high-density lipoprotein-cholesterol levels in obese men and women during weight reduction.


Journal Article

Levels of high-density lipoprotein-cholesterol (HDL-cholesterol) and other lipoproteins of 73 obese men and women were measured before and after a 16-week weight reduction program. There were significant differences between men and women. In men, a 10.7-kg weight loss was associated with a 5% increase in the HDL-cholesterol level, a 15.8% decrease in the low-density lipoprotein-cholesterol (LDL-cholesterol) level, and a 30.1% increase in the HDL-LDL ratio. Women, in contrast, showed an 8.9-kg weight loss, a 3.3% decrease in the HDL-cholesterol level, a 4.7% decrease in the LDL-cholesterol level, and no significant change in the HDL-LDL ratio. These differences suggest that weight raeduction may be an important means of improving plasma lipoprotein patterns in men but may be of more limited value in women.

Full Text

Duke Authors

Cited Authors

  • Brownell, KD; Stunkard, AJ

Published Date

  • August 1981

Published In

Volume / Issue

  • 141 / 9

Start / End Page

  • 1142 - 1146

PubMed ID

  • 7259372

Pubmed Central ID

  • 7259372

Electronic International Standard Serial Number (EISSN)

  • 1538-3679

International Standard Serial Number (ISSN)

  • 0003-9926

Digital Object Identifier (DOI)

  • 10.1001/archinte.141.9.1142


  • eng