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Narcotic use and misuse in Crohn's disease.

Publication ,  Journal Article
Crocker, JA; Yu, H; Conaway, M; Tuskey, AG; Behm, BW
Published in: Inflamm Bowel Dis
December 2014

BACKGROUND: The rate of narcotic misuse in the inflammatory bowel disease population is not well studied. The primary aim of this study was to determine in Crohn's disease (CD) whether a concurrent functional gastrointestinal disorder (FGID) was associated with increased rates of chronic narcotic use. Second, we aimed to identify potential risk factors for narcotic misuse. METHODS: A retrospective chart review of patients with CD followed at the University of Virginia's Gastroenterology Clinic from 2006 to 2011 was performed. The prescription monitoring program was accessed to confirm narcotic prescription filling histories. Narcotic misuse was defined as narcotic prescriptions filled from 4 or more prescribers and at 4 or more different pharmacies. RESULTS: Nine hundred thirty-one patients with CD were included in the study cohort. Eighty-seven (9.3%) patients were identified as having a concurrent FGID, and 192 (20%) were taking chronic narcotics. Patients with FGID were more likely to be taking chronic narcotics (44% versus 18%, P < 0.001). Thirty-seven percent (32/87) of patients with an FGID were misusing narcotics, compared with 9.6% (81/844) (P < 0.0001). Multivariate logistic regression demonstrated a significant association of misuse in patients with a concurrent FGID (odds ratio = 3.33, 95% confidence interval, 1.87-5.93). CONCLUSIONS: Twenty percent of patients with CD were using chronic narcotics with higher rates in those with FGID. Using the prescription monitoring program, a significant proportion of patients with CD with an FGID were misusing narcotics. We would recommend screening for narcotic misuse in patients with CD with a concomitant FGID and consider using prescription monitoring programs to identify others at risk for misuse.

Duke Scholars

Published In

Inflamm Bowel Dis

DOI

EISSN

1536-4844

Publication Date

December 2014

Volume

20

Issue

12

Start / End Page

2234 / 2238

Location

England

Related Subject Headings

  • Virginia
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Prognosis
  • Prevalence
  • Opioid-Related Disorders
  • Narcotics
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
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Crocker, J. A., Yu, H., Conaway, M., Tuskey, A. G., & Behm, B. W. (2014). Narcotic use and misuse in Crohn's disease. Inflamm Bowel Dis, 20(12), 2234–2238. https://doi.org/10.1097/MIB.0000000000000194
Crocker, Justin A., Huimin Yu, Mark Conaway, Anne G. Tuskey, and Brian W. Behm. “Narcotic use and misuse in Crohn's disease.Inflamm Bowel Dis 20, no. 12 (December 2014): 2234–38. https://doi.org/10.1097/MIB.0000000000000194.
Crocker JA, Yu H, Conaway M, Tuskey AG, Behm BW. Narcotic use and misuse in Crohn's disease. Inflamm Bowel Dis. 2014 Dec;20(12):2234–8.
Crocker, Justin A., et al. “Narcotic use and misuse in Crohn's disease.Inflamm Bowel Dis, vol. 20, no. 12, Dec. 2014, pp. 2234–38. Pubmed, doi:10.1097/MIB.0000000000000194.
Crocker JA, Yu H, Conaway M, Tuskey AG, Behm BW. Narcotic use and misuse in Crohn's disease. Inflamm Bowel Dis. 2014 Dec;20(12):2234–2238.
Journal cover image

Published In

Inflamm Bowel Dis

DOI

EISSN

1536-4844

Publication Date

December 2014

Volume

20

Issue

12

Start / End Page

2234 / 2238

Location

England

Related Subject Headings

  • Virginia
  • Severity of Illness Index
  • Risk Factors
  • Retrospective Studies
  • Prognosis
  • Prevalence
  • Opioid-Related Disorders
  • Narcotics
  • Middle Aged
  • Male