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An fMRI investigation of posttraumatic flashbacks.

Publication ,  Journal Article
Whalley, MG; Kroes, MCW; Huntley, Z; Rugg, MD; Davis, SW; Brewin, CR
Published in: Brain Cogn
February 2013

Flashbacks are a defining feature of posttraumatic stress disorder (PTSD), but there have been few studies of their neural basis. We tested predictions from a dual representation model of PTSD that, compared with ordinary episodic memories of the same traumatic event, flashbacks would be associated with activity in dorsal visual stream and related areas rather than in the medial temporal lobe. Participants with PTSD, with depression but not PTSD, and healthy controls were scanned during a recognition task with personally relevant stimuli. The contrast of flashbacks versus ordinary episodic trauma memories in PTSD was associated with increased activation in sensory and motor areas including the insula, precentral gyrus, supplementary motor area, and mid-occipital cortex. The same contrast was associated with decreased activation in the midbrain, parahippocampal gyrus, and precuneus/posterior cingulate cortex. The results were discussed in terms of theories of PTSD and dual-process models of recognition.

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Published In

Brain Cogn

DOI

EISSN

1090-2147

Publication Date

February 2013

Volume

81

Issue

1

Start / End Page

151 / 159

Location

United States

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Recognition, Psychology
  • Photic Stimulation
  • Perceptual Disorders
  • Middle Aged
  • Memory
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Experimental Psychology
 

Citation

APA
Chicago
ICMJE
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Whalley, M. G., Kroes, M. C. W., Huntley, Z., Rugg, M. D., Davis, S. W., & Brewin, C. R. (2013). An fMRI investigation of posttraumatic flashbacks. Brain Cogn, 81(1), 151–159. https://doi.org/10.1016/j.bandc.2012.10.002
Whalley, Matthew G., Marijn C. W. Kroes, Zoe Huntley, Michael D. Rugg, Simon W. Davis, and Chris R. Brewin. “An fMRI investigation of posttraumatic flashbacks.Brain Cogn 81, no. 1 (February 2013): 151–59. https://doi.org/10.1016/j.bandc.2012.10.002.
Whalley MG, Kroes MCW, Huntley Z, Rugg MD, Davis SW, Brewin CR. An fMRI investigation of posttraumatic flashbacks. Brain Cogn. 2013 Feb;81(1):151–9.
Whalley, Matthew G., et al. “An fMRI investigation of posttraumatic flashbacks.Brain Cogn, vol. 81, no. 1, Feb. 2013, pp. 151–59. Pubmed, doi:10.1016/j.bandc.2012.10.002.
Whalley MG, Kroes MCW, Huntley Z, Rugg MD, Davis SW, Brewin CR. An fMRI investigation of posttraumatic flashbacks. Brain Cogn. 2013 Feb;81(1):151–159.
Journal cover image

Published In

Brain Cogn

DOI

EISSN

1090-2147

Publication Date

February 2013

Volume

81

Issue

1

Start / End Page

151 / 159

Location

United States

Related Subject Headings

  • Stress Disorders, Post-Traumatic
  • Recognition, Psychology
  • Photic Stimulation
  • Perceptual Disorders
  • Middle Aged
  • Memory
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Experimental Psychology