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Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism?

Publication ,  Journal Article
Yoo, JY; Yip, L; Armstrong, MJ; Carty, SE; Kelley, ML; Stang, MT; McCoy, KL
Published in: Surgery
January 2016

BACKGROUND: Erectile dysfunction (ED) is a common diagnosis associated with age, hypertension, cardiovascular disease, and diabetes. Primary hyperparathyroidism (PHP) is also seen with these comorbidities, but its association with ED has yet to be studied. We evaluated the rate and resolution of impotence after curative surgery for PHP. METHODS: Prospectively collected data, including a self-reported questionnaire of symptoms, were reviewed for men who had curative parathyroid exploration for sporadic PHP from July 2010 to January 2014. Data were compared with an age-matched cohort of men who had thyroidectomy during the same period. RESULTS: Among 160 men with PHP and mean age of 60 years (range, 19-88), preoperative ED was reported by 13%, and this group was older than patients without ED (mean age, 70 vs 58 years, P < .01). Self-reported resolution of ED after parathyroidectomy occurred in 67% compared with 43% of patients in a thyroidectomy cohort. Preoperative mean arterial blood pressure was less in men with postoperative resolution of ED (96.6 vs 105.4 mm Hg, P = .03). Among 3 of 21 men on specific ED medications, 2 no longer required them postoperatively. CONCLUSION: Impotence is reported often by men undergoing parathyroidectomy for PHP. After curative surgery, 67% of those affected may self-report ED resolution, which may be more pronounced in those patients with a lesser preoperative mean arterial blood pressure.

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Published In

Surgery

DOI

EISSN

1532-7361

Publication Date

January 2016

Volume

159

Issue

1

Start / End Page

204 / 210

Location

United States

Related Subject Headings

  • Young Adult
  • Surgery
  • Retrospective Studies
  • Parathyroidectomy
  • Middle Aged
  • Male
  • Hyperparathyroidism, Primary
  • Humans
  • Erectile Dysfunction
  • Aged, 80 and over
 

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Yoo, J. Y., Yip, L., Armstrong, M. J., Carty, S. E., Kelley, M. L., Stang, M. T., & McCoy, K. L. (2016). Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism? Surgery, 159(1), 204–210. https://doi.org/10.1016/j.surg.2015.06.055
Yoo, Jenny Y., Linwah Yip, Michaele J. Armstrong, Sally E. Carty, Meghan L. Kelley, Michael T. Stang, and Kelly L. McCoy. “Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism?Surgery 159, no. 1 (January 2016): 204–10. https://doi.org/10.1016/j.surg.2015.06.055.
Yoo JY, Yip L, Armstrong MJ, Carty SE, Kelley ML, Stang MT, et al. Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism? Surgery. 2016 Jan;159(1):204–10.
Yoo, Jenny Y., et al. “Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism?Surgery, vol. 159, no. 1, Jan. 2016, pp. 204–10. Pubmed, doi:10.1016/j.surg.2015.06.055.
Yoo JY, Yip L, Armstrong MJ, Carty SE, Kelley ML, Stang MT, McCoy KL. Does impotence improve after parathyroidectomy in men with primary hyperparathyroidism? Surgery. 2016 Jan;159(1):204–210.
Journal cover image

Published In

Surgery

DOI

EISSN

1532-7361

Publication Date

January 2016

Volume

159

Issue

1

Start / End Page

204 / 210

Location

United States

Related Subject Headings

  • Young Adult
  • Surgery
  • Retrospective Studies
  • Parathyroidectomy
  • Middle Aged
  • Male
  • Hyperparathyroidism, Primary
  • Humans
  • Erectile Dysfunction
  • Aged, 80 and over