Recruitment and Retention for a Weight Loss Maintenance Trial Involving Weight Loss Prior to Randomization.


Journal Article

OBJECTIVE: A weight loss maintenance trial involving weight loss prior to randomization is challenging to implement due to the potential for dropout and insufficient weight loss. We examined rates and correlates of non-initiation, dropout, and insufficient weight loss during a weight loss maintenance trial. METHODS: The MAINTAIN trial involved a 16-week weight loss program followed by randomization among participants losing at least 4 kg. Psychosocial measures were administered during a screening visit. Weight was obtained at the first group session and 16 weeks later to determine eligibility for randomization. RESULTS: Of 573 patients who screened as eligible, 69 failed to initiate the weight loss program. In adjusted analyses, failure to initiate was associated with lower age, lack of a support person, and less encouragement for making dietary changes. Among participants who initiated, 200 dropped out, 82 lost insufficient weight, and 222 lost sufficient weight for randomization. Compared to losing sufficient weight, dropping out was associated with younger age and tobacco use, whereas losing insufficient weight was associated with non-White race and controlled motivation for physical activity. CONCLUSIONS: Studies should be conducted to evaluate strategies to maximize recruitment and retention of subgroups that are less likely to initiate and be retained in weight loss maintenance trials.

Full Text

Duke Authors

Cited Authors

  • Voils, CI; Grubber, JM; McVay, MA; Olsen, MK; Bolton, J; Gierisch, JM; Taylor, SS; Maciejewski, ML; Yancy, WS

Published Date

  • December 2016

Published In

Volume / Issue

  • 2 / 4

Start / End Page

  • 355 - 365

PubMed ID

  • 28090340

Pubmed Central ID

  • 28090340

International Standard Serial Number (ISSN)

  • 2055-2238

Digital Object Identifier (DOI)

  • 10.1002/osp4.58


  • eng

Conference Location

  • United States