De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation.

Journal Article (Journal Article;Review)

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developing countries. Approximately 25% of patients with NAFLD develop nonalcoholic steatohepatitis (NASH). NASH-related cirrhosis is now a leading listing indication for liver transplantation in the United States. Although posttransplant survival for NASH-related cirrhosis is comparable with that of other liver diseases, many patients have features of metabolic syndrome, which can contribute to a recurrence of NAFLD or NASH. This article reviews the epidemiology, pathophysiology, and treatment of de novo and recurrence of NASH after liver transplantation.

Full Text

Duke Authors

Cited Authors

  • Kappus, M; Abdelmalek, M

Published Date

  • May 2017

Published In

Volume / Issue

  • 21 / 2

Start / End Page

  • 321 - 335

PubMed ID

  • 28364816

Electronic International Standard Serial Number (EISSN)

  • 1557-8224

Digital Object Identifier (DOI)

  • 10.1016/j.cld.2016.12.006

Language

  • eng

Conference Location

  • United States