De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation.

Published

Journal Article (Review)

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in developing countries. Approximately 25% of patients with NAFLD develop nonalcoholic steatohepatitis (NASH). NASH-related cirrhosis is now a leading listing indication for liver transplantation in the United States. Although posttransplant survival for NASH-related cirrhosis is comparable with that of other liver diseases, many patients have features of metabolic syndrome, which can contribute to a recurrence of NAFLD or NASH. This article reviews the epidemiology, pathophysiology, and treatment of de novo and recurrence of NASH after liver transplantation.

Full Text

Duke Authors

Cited Authors

  • Kappus, M; Abdelmalek, M

Published Date

  • May 2017

Published In

Volume / Issue

  • 21 / 2

Start / End Page

  • 321 - 335

PubMed ID

  • 28364816

Pubmed Central ID

  • 28364816

Electronic International Standard Serial Number (EISSN)

  • 1557-8224

Digital Object Identifier (DOI)

  • 10.1016/j.cld.2016.12.006

Language

  • eng

Conference Location

  • United States