Skip to main content

The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae.

Publication ,  Journal Article
Osorio, CG; Martinez-Wilson, H; Camilli, A
Published in: J Bacteriol
August 2004

We made single and combined mutations in ompU, ompT, and the two putative porin genes vca1008 and vc0972. The fitness of the strains was tested in vitro and in the infant mouse model of intestinal infection. We also studied the transcriptional induction of vca1008 in vitro and during mouse infection. We show that vca1008 is induced during infection and is necessary and sufficient (in the absence of ompU, ompT, and vc0972) for infection.

Duke Scholars

Published In

J Bacteriol

DOI

ISSN

0021-9193

Publication Date

August 2004

Volume

186

Issue

15

Start / End Page

5167 / 5171

Location

United States

Related Subject Headings

  • Virulence
  • Vibrio cholerae
  • Transcription, Genetic
  • Microbiology
  • Mice
  • Intestine, Small
  • Humans
  • Gene Expression Regulation, Bacterial
  • Culture Media
  • Cholera
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Osorio, C. G., Martinez-Wilson, H., & Camilli, A. (2004). The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae. J Bacteriol, 186(15), 5167–5171. https://doi.org/10.1128/JB.186.15.5167-5171.2004
Osorio, Carlos G., Hector Martinez-Wilson, and Andrew Camilli. “The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae.J Bacteriol 186, no. 15 (August 2004): 5167–71. https://doi.org/10.1128/JB.186.15.5167-5171.2004.
Osorio CG, Martinez-Wilson H, Camilli A. The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae. J Bacteriol. 2004 Aug;186(15):5167–71.
Osorio, Carlos G., et al. “The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae.J Bacteriol, vol. 186, no. 15, Aug. 2004, pp. 5167–71. Pubmed, doi:10.1128/JB.186.15.5167-5171.2004.
Osorio CG, Martinez-Wilson H, Camilli A. The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae. J Bacteriol. 2004 Aug;186(15):5167–5171.

Published In

J Bacteriol

DOI

ISSN

0021-9193

Publication Date

August 2004

Volume

186

Issue

15

Start / End Page

5167 / 5171

Location

United States

Related Subject Headings

  • Virulence
  • Vibrio cholerae
  • Transcription, Genetic
  • Microbiology
  • Mice
  • Intestine, Small
  • Humans
  • Gene Expression Regulation, Bacterial
  • Culture Media
  • Cholera